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Wiskott–Aldrich Syndrome at the nexus of autoimmune and primary immunodeficiency diseases

✍ Scribed by Sophia Y. Cleland; Richard M. Siegel


Book ID
113622787
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
358 KB
Volume
585
Category
Article
ISSN
0014-5793

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Characterization of the Wiskott-Aldrich
✍ Shigeaki Nonoyama; Hans D Ochs 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 784 KB

Wiskott-Aldrich syndrome is an X-linked disorder characterized by thrombocytopenia, eczema and immunodeficiency. The Wiskott-Aldrich syndrome protein and the gene that encodes it have been identified by positional cloning and the protein has been shown to contain a pleckstrin-homology domain, a GTPa