## Abstract Activated glial cells have been implicated in the neuropathogenesis of many infectious and inflammatory diseases of the brain. A number of inflammatory mediators have been proposed to play a role in glial cellβrelated brain damage; e.g., free radicals such as nitric oxide (NO), cytokine
WIN55,212-2-Mediated Inhibition of HIV-1 Expression in Microglial Cells: Involvement of Cannabinoid Receptors
β Scribed by Rock, R. Bryan; Gekker, Genya; Hu, Shuxian; Sheng, Wen S.; Cabral, Guy A.; Martin, Billy R.; Peterson, Phillip K.
- Book ID
- 107380573
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 153 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1557-1890
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Cannabinoids regulate numerous physiological and pathological events like inflammation or neurodegeneration via CB(1) and CB(2) receptors. The mechanisms behind cannabinoid effects show a high variability and may also involve transient receptor potential channels (TRP) and N-type voltage-gated Ca(2+
## Abstract The endogenous cannabinoid system is involved in the regulation of a number of physiologic effects in both the central and peripheral nervous systems. Its role in the control of neuronal cell proliferation has attracted major attention because of its potential implications for new thera