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Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene

✍ Scribed by Huff, Vicki


Book ID
109948686
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
388 KB
Volume
11
Category
Article
ISSN
1474-1776

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Two molecular pathways leading to cancer are known. Common-type cancers arise from the 'tumour suppressor' pathway, characterized by gross chromosomal changes and allelic losses (LOH) in an average of 25 per cent or more of randomly chosen chromosomal loci. The 'mutator pathway' has been recognized