Homozygous intragenic deletion in the WT
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Elizabeth M. Algar; Mark T. Kenney; Lisa A. Simms; Shirley I. Smith; Yoshiki Kid
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Article
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1995
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John Wiley and Sons
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English
⚖ 859 KB
Communicated by R. G. H. Cotton We have examined a panel of 21 sporadic Wilms' tumours for rearrangements in the Wilms' tumour suppressor gene, WT1. In one tumour with specific allele loss in chromosome llp13, a homozygous deletion in the 3' end of the gene, encompassing exon 10 and the 3' untransla