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Wilms Tumor Gene (WT1) Expression as a Panleukemic Marker

✍ Scribed by Hans D. Menssen; Jan M. Siehl; Eckhard Thiel

Publisher
Carden Jennings Publishing
Year
2002
Tongue
English
Weight
107 KB
Volume
76
Category
Article
ISSN
0925-5710

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## Abstract We report expression of the __wt__ I (Wilms' tumor) gene by cultured human melanoma cells. Using RNA polymerase chain reaction analysis, __wt__ I transcripts were detected in 7 of 9 melanoma cell lines but not in 5 normal melanocyte strains. In Northern blot analysis, steady‐state __wt_