Mutations in the WTI tumor suppressor gene are known t o contribute t o the development of Wilms' tumor (WT) and associated gonadal abnormalities. WTI is expressed principally in the fetal kidney, developing gonads, and spleen and also in the mesothelium, which lines the coelomic cavities. These tis
✦ LIBER ✦
Wilms’ tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells
✍ Scribed by Vidovic, K; Svensson, E; Nilsson, B; Thuresson, B; Olofsson, T; Lennartsson, A; Gullberg, U
- Book ID
- 109887362
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 547 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0887-6924
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