Wilms tumor and autoimmune neutropenia
β Scribed by Trebo, Monika M.; Thorner, Paul S.; Weitzman, Sheila
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 58 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0098-1532
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Wilms tumor (WT), a sporadic and familial childhood kidney tumor, is genetically heterogeneous. One WT gene, WT1 at 11p13, has been cloned, but only a minority of WTs carry detectable mutations at that locus. WT1 can also be excluded as the predisposition gene in most WT families, implying the exist
## Abstract Wilms tumor (WT), an embryonic tumor arising from undifferentiated renal mesenchyme, has been a productive model for understanding the role of genes in both tumorigenesis and normal organogenesis. Approximately 2% of WT patients have a family history of WT, and even sporadic WT is thoug