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Will a three-allele model of inheritance explain the HLA data for Type 1 (insulin-dependent) diabetes?

โœ Scribed by D. A. Greenberg

Publisher
Springer
Year
1985
Tongue
English
Weight
528 KB
Volume
28
Category
Article
ISSN
0012-186X

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Allele-specific gene probing supports th
Allele-specific gene probing supports the DQ molecule as a determinant of inherited susceptibility to Type 1 (insulin-dependent) diabetes mellitus
โœ D. Jenkins; C. Mijovic; K. H. Jacobs; M. A. Penny; J. Fletcher; A. H. Barnett ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 633 KB

Trans-racial analysis of disease associations has improved mapping of MHC-linked susceptibility to Type 1 (insulin-dependent) diabetes mellitus. In this study the contributions of the MHC class II DQA1 and DQB1 genes were investigated. Sequence-specific oligonucleotide gene probing in Type 1 diabeti