Adenovirus-mediated wild-type-p53-gene e
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Vladimir A. Shatrov; Maya Ameyar; CΓ©line Bouquet; Zhenzi Cai; Rodica Stancou; He
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Article
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2000
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John Wiley and Sons
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French
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We have shown that the loss of p53 function contributed to resistance of tumor cells to TNF-induced cytotoxicity. In the present study, we evaluated the effect of wild-type p53 (wt-p53) expression on TNF sensitivity, by introducing wt-p53 into MCF7/Adr cells in which p53 was deleted, via a recombina