๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Why do tumor cells have a high aerobic glycolysis?

โœ Scribed by Efraim Racker

Book ID
102309243
Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
347 KB
Volume
89
Category
Article
ISSN
0021-9541

No coin nor oath required. For personal study only.

โœฆ Synopsis

Abstract

In Ehrlich ascites cells and several other tumors, the high aerobic glycolysis is maintained by generation of ADP and P~i~ by the plasma membrane Na^+^K^+^ ATPase. The high ATPase activity is caused by a defective pump that operates at a low efficiency. Studies of the mechanism of action of the Na^+^K^+^ ATPase and other pump ATPases suggest several alternative mechanisms that might account for the decreased efficiency. The possibility of involvement of a proteolipid is under investigation.

๐Ÿ“œ SIMILAR VOLUMES

Why do cancers have high aerobic glycoly
Why do cancers have high aerobic glycolysis?
โœ Gatenby, Robert A.; Gillies, Robert J. ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 519 KB
Allorestricted T lymphocytes with a high
Allorestricted T lymphocytes with a high avidity T-cell receptor towards NY-ESO-1 have potent anti-tumor activity
โœ Holger Krรถnig; Kathrin Hofer; Heinke Conrad; Philippe Guilaume; Julia Mรผller; Ma ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 321 KB

## Abstract The cancerโ€testis antigen NYโ€ESOโ€1 has been targeted as a tumorโ€associated antigen by immunotherapeutical strategies, such as cancer vaccines. The prerequisite for a Tโ€cellโ€based therapy is the induction of T cells capable of recognizing the NYโ€ESOโ€1โ€expressing tumor cells. In this stud

Promotability and tissue specificity of
Promotability and tissue specificity of hereditary cancer genes: Do hereditary cancer patients have a reduced requirement for tumor promotion because all their somatic cells are heterozygous at the predisposing locus?
โœ Christos Paraskeva; Ann C. Williams ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 461 KB

## INITIATION/PROMOTION AND TUMOR SUPPRESSION Two important concepts in carcinogenesis have stimulated major research programs that have led to significant progress in our understanding of the cellular and molecular basis of cancer. The first is the multistage nature of carcinogenesis and the sepa