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Whole-Genome Amplification by Single-Cell Comparative Genomic Hybridization PCR (SCOMP)

✍ Scribed by Arneson, N.; Hughes, S.; Houlston, R.; Done, S.


Book ID
125481383
Publisher
Cold Spring Harbor Laboratory Press
Year
2008
Tongue
English
Weight
110 KB
Volume
2008
Category
Article
ISSN
1940-3402

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## Abstract Nuclear variation in size and shape and genomic instability are hallmarks of dedifferentiated cancer cells. Although micronuclei are a typical long‐term consequence of DNA damage, their contribution to chromosomal instability and clonal diversity in cancer disease is unclear. We isolate