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White matter lesions on magnetic resonance imaging in late-life depression

✍ Scribed by Byoung Hoon OH; Jin Sook CHEON


Book ID
109058869
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
90 KB
Volume
4
Category
Article
ISSN
1346-3500

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## Abstract ## Purpose To examine the relationships between the damaged macromolecular pool seen on magnetization transfer (MT) imaging and cerebral metabolic changes recorded by magnetic resonance spectroscopy (MRS), in frontal white and gray matter regions of late‐life MDD patients. ## Material

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## Abstract ## Background Decreased caudate volumes and increased white matter lesions (WMLs) are associated both with aging and late‐life depression, but the relationship between the two is unclear. We examined the association between WML and caudate volume, hypothesizing there would be a negativ