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White matter lesions in the elderly: Pathophysiological hypothesis on the effect on brain plasticity and reserve

✍ Scribed by Samantha Galluzzi; Cristina Lanni; Leonardo Pantoni; Massimo Filippi; Giovanni B. Frisoni

Book ID
119302753
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
605 KB
Volume
273
Category
Article
ISSN
0022-510X

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## Abstract ## Purpose: To develop an automated lesion‐filling technique (LEAP; LEsion Automated Preprocessing) that would reduce lesion‐associated brain tissue segmentation bias (which is known to affect automated brain gray [GM] and white matter [WM] tissue segmentations in people who have multi