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White matter changes and late-life depressive symptoms: Longitudinal study

✍ Scribed by Teodorczuk, A.; O'brien, J. T.; Firbank, M. J.; Pantoni, L.; Poggesi, A.; Erkinjuntti, T.; Wallin, A.; Wahlund, L.-O.; Gouw, A.; Waldemar, G.; Schmidt, R.; Ferro, J. M.; Chabriat, H.; Bazner, H.; Inzitari, D.

Book ID
118226059
Publisher
The Royal College of Psychiatrists
Year
2007
Tongue
English
Weight
390 KB
Volume
191
Category
Article
ISSN
0007-1250

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Depressive symptoms and white matter cha
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Objective The aim of the present study was to investigate if depressive symptoms in demented patients are associated with white matter changes (WMCs) in the brain. Background WMCs are frequently found in patients with dementia, as well as among elderly nondemented patients with depressive symptoms.

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## Abstract ## Background Decreased caudate volumes and increased white matter lesions (WMLs) are associated both with aging and late‐life depression, but the relationship between the two is unclear. We examined the association between WML and caudate volume, hypothesizing there would be a negativ