When Should Clinicians Order Genetic Testing for Dravet Syndrome?

Order-restricted Scores Test for the Eva

Order-restricted Scores Test for the Evaluation of Population-based Case–control Studies when the Genetic Model is Unknown

✍ Ludwig A. Hothorn; Torsten Hothorn 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 2 views

## Abstract The Cochran–Armitage (CA) linear trend test for proportions is often used for genotype‐based analysis of candidate gene association. Depending on the underlying genetic mode of inheritance, the use of model‐specific scores maximises the power. Commonly, the underlying genetic model, __i