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Wheel-running in a transgenic mouse model of Alzheimer's disease: Protection or symptom?

✍ Scribed by Helene Richter; Oliver Ambrée; Lars Lewejohann; Arne Herring; Kathy Keyvani; Werner Paulus; Rupert Palme; Chadi Touma; Wolf-Rüdiger Schäbitz; Norbert Sachser

Book ID
116284930
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
838 KB
Volume
190
Category
Article
ISSN
0166-4328

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## Abstract The cerebral deposition of amyloid β‐peptide, a central event in Alzheimer's disease (AD) pathogenesis, begins several years before the onset of clinical symptoms. Noninvasive detection of AD pathology at this initial stage would facilitate intervention and enhance treatment success. In