✦ LIBER ✦

Wheat Germ Agglutinin Functionalized Complexation Hydrogels for Oral Insulin Delivery

✍ Scribed by Wood, Kristy M.; Stone, Gregory M.; Peppas, Nicholas A.

Book ID: 125806562
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 349 KB
Volume: 9
Category: Article
ISSN: 1525-7797
DOI: 10.1021/bm701274p

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Lectin functionalized complexation hydro

Lectin functionalized complexation hydrogels for oral protein delivery

✍ K.M. Wood; G. Stone; N.A. Peppas 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 182 KB

Cyclodextrin complexed insulin encapsula

Cyclodextrin complexed insulin encapsulated hydrogel microparticles: An oral delivery system for insulin

✍ S. Sajeesh; K. Bouchemal; V. Marsaud; C. Vauthier; Chandra P. Sharma 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 619 KB

Cellular Evaluation of Synthesized Insul

Cellular Evaluation of Synthesized Insulin/Transferrin Bioconjugates for Oral Insulin Delivery Using Intelligent Complexation Hydrogels

✍ Justin P. Shofner; Margaret A. Phillips; Nicholas A. Peppas 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB

## Abstract Insulin transport across the epithelial cell layer in the small intestine was studied using insulin/transferrin conjugates with and without the presence of P(MAA__‐g‐__EG) microparticles in contact with a co‐culture of Caco‐2/HT29‐MTX cells. The insulin/transferrin conjugate was shown t

Synthesis, Characterization andIn VivoEf

Synthesis, Characterization andIn VivoEfficacy of PEGylated Insulin for Oral Delivery with Complexation Hydrogels

✍ Anthony D. Tuesca; Collin Reiff; Jeffrey I. Joseph; Anthony M. Lowman 📂 Article 📅 2009 🏛 Springer US 🌐 English ⚖ 444 KB

Complexation hydrogels for oral insulin

Complexation hydrogels for oral insulin delivery: Effects of polymer dosing on in vivo efficacy

✍ Anthony Tuesca; Koji Nakamura; Mariko Morishita; Jeffrey Joseph; Nicholas Peppas 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 225 KB

Hydrogels comprised of poly(methacrylic acid) grafted with poly(ethylene glycol) (P(MAA-g-EG)) were characterized and examined for their potential as oral insulin carriers. Insulin loaded polymer (ILP) samples were made using two different polymer formulations. The values for the effective molecular

Thiol functionalized polymethacrylic aci

Thiol functionalized polymethacrylic acid-based hydrogel microparticles for oral insulin delivery

✍ S. Sajeesh; C. Vauthier; C. Gueutin; G. Ponchel; Chandra P. Sharma 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 613 KB

In the present study thiol functionalized polymethacrylic acid-polyethylene glycol-chitosan (PCP)-based hydrogel microparticles were utilized to develop an oral insulin delivery system. Thiol modification was achieved by grafting cysteine to the activated surface carboxyl groups of PCP hydrogels (Cy