What's new: Conditional cell ablation in Drosophila

✍ Scribed by J. W. Sentry; M. M. Yang; K. Kaiser

• Book ID: 101712572
• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 395 KB
• Volume: 15
• Category: Article
• ISSN: 0265-9247
• DOI: 10.1002/bies.950150710

✦ Synopsis

Targeting of cell ablation agents under the control of tissue-specific promoters promises to be an important tool for studies of development and function in higher organisms. Temperature-sensitive cell ablation agents, recently developed for Drosophila, extend control to temporal as well as spatial aspects of toxin expression. Here we discuss achievements to date, together with a novel form of enhancer trap technology with the potential for driving toxin expression in a large range of cell types.