What turns CREB on?
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Mona Johannessen; Marit Pedersen Delghandi; Ugo Moens
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Article
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2004
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Elsevier Science
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English
⚖ 328 KB
The transactivation domain of the cAMP response element-binding protein (CREB) consists of two major domains. The glutamine-rich Q2 domain, which interacts with the general transcription factor TAFII130/135, is sufficient for the recruitment of a functional RNA polymerase II complex and allows basal