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What the papers say: Cystic fibrosis: Prospects for therapy

โœ Scribed by David J. Porteous; Eric W. F. W. Alton


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
303 KB
Volume
15
Category
Article
ISSN
0265-9247

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The complex process of cell immortalization and transformation is likely to involve the inactivation of growth regulatory genes. Mutations (deletions, missense mutations) in the p53 gene are the most frequently observed genetic alteration in human tumors, making p53 a candidate for a cellular protei