𝔖 Bobbio Scriptorium
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What the papers say: A puff is born

✍ Scribed by Pierre Spierer

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
291 KB
Volume
4
Category
Article
ISSN
0265-9247

No coin nor oath required. For personal study only.

✦ Synopsis

Pujfing of polytene chromosomes is associated with intense genetic activity. Genetic determinants of puffing in Drosophila can now be dissected by transplanting genes known to puff to other chromosomal locations by transposonmediated germ line transformation. Recent studies show that induction of a heat shock p u f requires only about one hundred and jifty base pairs of DNA upstream of the gene, around the start of transcription, and not the protein coding sequence itself. Moreover, the size of the ectopic' p u f was found to be related to the size of the corresponding transcript. Similar work is now in progress with hormonally-controlled puffs.

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