✦ LIBER ✦

What the clinician can learn from MRS lactate measurements

✍ Scribed by James W. Prichard

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 446 KB
Volume: 4
Category: Article
ISSN: 0952-3480
DOI: 10.1002/nbm.1940040212

No coin nor oath required. For personal study only.

✦ Synopsis

Cedar St. New Haven C T 06510, USA Lactate is of special importance in brain metabolism. In the 198Os, noninvasive methods for measurement of lactate concentration and turnover rate in living brain by 'H and '% NMR spectroscopy were implemented in both animals and humans, opening the way to innovative examination of lactate's role in normal and deranged brain function. Early data on elevation of lactate in human visual cortex by physiologic stimulation and turnover of pathologically elevated brain lactate pools in animals and humans suggest that the new methods are likely to benefit clinical practice both directly-by providing information useful in management of individual patientsand indirectly-through improved understanding of disease processes.

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