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What is the impact of disease prevalence upon health technology assessment?

✍ Scribed by Rotily, Michel; Roze, Stéphane

Book ID: 123197241
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 889 KB
Volume: 27
Category: Article
ISSN: 1521-6918
DOI: 10.1016/j.bpg.2013.08.018

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## Abstract Huntington's disease (HD) is a neurodegenerative disease caused by a cytosine adenosine guanine (CAG) expansion in the __huntingtin__ gene. The length of the triplet repeat is the most important factor in determining age of onset and the severity of the disease, but substantial variabil