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What is a significant score change on the mini-mental state examination?

✍ Scribed by Ben Schmand; Jaap Lindeboom; Lenore Launer; Marc Dinkgreve; Chris Hooijer; Cees Jonker

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
297 KB
Volume
10
Category
Article
ISSN
0885-6230

No coin nor oath required. For personal study only.

✦ Synopsis

The distribution of change scores of the Mini-Mental State Examination (MMSE) was assessed in healthy aged subjects after an interval of 1 year. As part of the Amsterdam Study of the Elderly, which is a community survey on ageing and cognitive decline (N = 4051; age range 65-84), a subsample of subjects ( N = 247) was studied twice.

Participants with dementia, other psychiatric disorders or physical disease which might interfere with cognitive testing were excluded. Test-retest reliability was 0.55 in this group. The distribution of change scores ranged from -9 to +5. From this result the following clinical rule-of-thumb was derived. In an individual patient, and in the absence of other indications of a dementing process, a deterioration in MMSE score must be greater than five points after 1 year to be suspect for a genuine cognitive decline.

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