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What are the Clinically Important Consequences of ESRD-Associated Endocrine Dysfunction?

✍ Scribed by Louis F. Amorosa


Book ID
109082234
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
427 KB
Volume
10
Category
Article
ISSN
0894-0959

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## Abstract X‐box binding protein 1 (XBP‐1) is stimulated by endoplasmic reticulum stress as part of the unfolded protein response (UPR), which can promote apoptosis or cell survival. Non‐conventional splicing, stimulated during the UPR, converts mRNA for “unspliced” XBP‐1U to “spliced” XBP‐1S mRNA