What have animal models taught us about
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Guillermina Lozano; Gerard P Zambetti
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Article
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2005
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John Wiley and Sons
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English
β 228 KB
## Abstract Mouse models have provided important insight into the __in vivo__ significance of upstream and downstream signals that regulate the __p53__ tumour suppressor. One important lesson learned from these models is that negative regulators of p53 are critical __in vivo__ modulators of p53 act