๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Wet-granulation research with application to scale-up

โœ Scribed by Gabriel I. Tardos

Publisher
Elsevier
Year
2005
Tongue
English
Weight
363 KB
Volume
3
Category
Article
ISSN
1672-2515

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Steady states in granulation of pharmace
Steady states in granulation of pharmaceutical powders with application to scale-up
โœ James N. Michaels; Leon Farber; Gordon S. Wong; Karen Hapgood; Stephen J. Heidel ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 915 KB

Theoretical and experimental evidence is given to show that steady states can be reached during agglomerate growth and break-up in high-shear granulation of fine powders. An earlier theoretical model [G.I. Tardos, I.M. Khan and P.R. Mort, Critical parameters and limiting conditions in binder granula

Formulation development and process scal
Formulation development and process scale up of a high shear wet granulation formulation containing a poorly wettable drug
โœ Xiaorong He; Keith A. Lunday; Liang-chi Li; Mark J. Sacchetti ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 300 KB

Aplaviroc 200 mg tablets were made by a high shear wet granulation process. A formulation and process DOE were carried out to define formulation and process parameters at pilot scale in GSKs R&D facility. During the scale up, several batches made at the production facility dissolved slower than the

Scale up of a viscous fungal fermentatio
Scale up of a viscous fungal fermentation: Application of scale-up criteria with regime analysis and operating boundary conditions
โœ D.J. Pollard; T.F. Kirschner; G.R. Hunt; I.-T. Tong; R. Stieber; P.M. Salmon ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 404 KB ๐Ÿ‘ 1 views

## Abstract The scale up of the novel, pharmaceutically important pneumocandin (B~0~), from the filamentous fungus __Glarea lozoyensis__ was successfully completed from pilot scale (0.07, 0.8, and 19 m^3^) to production scale (57 m^3^). This was accomplished, despite dissimilar reactor geometry, em