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Werner syndrome: Molecular genetics and mechanistic hypotheses

✍ Scribed by Raymond J. Monnat Jr.


Book ID
113371304
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
541 KB
Volume
27
Category
Article
ISSN
0531-5565

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Hypothesis: Werner syndrome and biologic
✍ Ray Thweatt; Samuel Goldstein πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 747 KB

Werner syndrome (WS) is an inherited disorder that produces somatic stunting, premature ageing and early onset of degenerative and neoplastic diseases. Cultured fibroblasts derived from subjects with W-S are found to undergo premature replicative senescence and thus provide a cellular model system t