Well-differentiated extraskeletal osteosarcoma: Report of 2 cases, 1 with dedifferentiation
β Scribed by Luigia C. Abramovici; Prodromos Hytiroglou; Robert M. Klein; Georgios Karkavelas; Antonios Drevelegas; Eugenia Panousi; German C. Steiner
- Book ID
- 116533906
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 411 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1532-8392
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## Abstract The __MDM2__ and __CDK4__ genes are the main targets of chromosome 12 amplification in wellβdifferentiated and dedifferentiated liposarcomas. Nevertheless, around 10% of these tumors do not amplify __CDK4__. To find substitutive alterations of __CDK4__ amplification, we analyzed a large