Weight reduction and improved glycaemic control following oestrogen replacement: individualising diabetes care in women
✍ Scribed by Dalvi, S ;Khanolkar, M ;Biswas, M
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 463 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1357-8170
- DOI
- 10.1002/pdi.1478
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✦ Synopsis
Abstract
Post‐menopausal oestrogen deficiency symptoms may cause mood disturbances and affect compliance, yet clinicians are reluctant to prescribe oestrogen replacement in view of adverse risks.
A 51‐year‐old woman was referred with poor glycaemic control. Compliance with diet and medications was poor. Intercurrent problems included depression, dyslipidaemia and severe vasomotor symptoms following hysterectomy one year prior.
HbA~1c~ was 12.4%; fasting total cholesterol 5.92mmol/L (NR 2.5–5). The patient was prescribed oestrogen replacement and no adjustments were made to diet or insulin. Over several months, mood and energy improved and weight fell from 110kg to 81kg, HbA~1c~ dropped to 7.6%, cholesterol was 2.56mmol/L and insulin dosage halved.
The impact of menopausal symptoms on health and wellbeing is often underestimated. In selected post‐menopausal women with type 2 diabetes, short‐term treatment with hormone replacement therapy may be useful if benefits obtained outweigh potential risks. Copyright © 2010 John Wiley & Sons.