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WDR5 Associates with Histone H3 Methylated at K4 and Is Essential for H3 K4 Methylation and Vertebrate Development

✍ Scribed by Joanna Wysocka; Tomek Swigut; Thomas A. Milne; Yali Dou; Xin Zhang; Alma L. Burlingame; Robert G. Roeder; Ali H. Brivanlou; C. David Allis


Book ID
116352608
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
899 KB
Volume
121
Category
Article
ISSN
0092-8674

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Differential dynamics of histone H3 meth
✍ Konstantin Lepikhov; JΓΆrn Walter πŸ“‚ Article πŸ“… 2004 πŸ› BioMed Central 🌐 English βš– 623 KB

## Background In the mouse zygote the paternal genome undergoes dramatic structural and epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and DNA is rapidly and actively demethylated. The epigenetic asymmetry between parental genomes remains at least until the 2-cell