Ways to discern the presynaptic effect of drugs on neurotransmitter release
β Scribed by Hanna Parnas; Lee A. Segel
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 1023 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0022-5193
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The effect of verapamil on resting and depolarizationinduced monoamine release was investigated in rat hippocampal synaptosomes prelabeled with [3H]-5hydroxytryptamine (HT) or [3H]-norepinephrine (NE) and rat striatal synaptosomes prelabeled with [3H]-dopamine (DA). Verapamil (50 pM) completely abol
Release of transmitter substances during synaptic communication in a biological process of great importance, and it is worthwhile to ascertain the basic molecular events underlying this process. We present a minimal model of synaptic vesicle (SV) dynamics, with which most of the major experimentally