Ways of inhibition of cholesterol biosynthesis by cortisol in the rat liver
โ Scribed by V. N. Titov; V. M. Sanfirova; G. A. Zhurzhina
- Publisher
- Springer US
- Year
- 1981
- Tongue
- English
- Weight
- 302 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0007-4888
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๐ SIMILAR VOLUMES
## Abstract A single dose of 1 mg hydrocortisone per rat stimulates the incorporation of labeled acetate into the cholesterol of the liver by a factor of 2.7 measured 18 hours after the administration of the hormone and 2 hours after the tracer dose of labeled acetate.
cholesterol levels. Thus, inhibiting late cholesterol syn-The conversion of 7-dehydrocholesterol to cholesterol thesis hinders growth of rapidly enlarging malignant is the last reaction in the cholesterol biosynthesis pathtumors. (HEPATOLOGY 1996;24:440-445.) way catalyzed by the microsomal enzyme,