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WAVELENGTH DEPENDENCE OF DNA INCISION BY A HUMAN ULTRAVIOLET ENDONUCLEASE

✍ Scribed by PATRICIA E. GALLAGHER; RANDI B. WEISS; THOMAS P. BRENT; NAHUM J. DUKER


Book ID
114895570
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
443 KB
Volume
49
Category
Article
ISSN
0031-8655

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A Human Endonuclease Incises Ultraviolet
✍ Patricia E. Gallagher; Randi B. Weiss; Thomas P. Brent; Nahum J. Duker πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 359 KB

Both ultraviolet irradiation and oxidation of DNA produce a variety of pyrimidine base damages. A human endonuclease recognizes such altered bases on these DNA substrates. This human endonuclease incises ultraviolet-irradiated DNA exclusively at sites of photochemically modified cytosines. The preci