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Water Solvent Method for Esterification and Amide Formation Between Acid Chlorides and Alcohols Promoted by Combined Catalytic Amines: Synergy Between N-Methylimidazole and N,N,N′,N′-Tetramethylethylenediamine (TMEDA).

✍ Scribed by Hidefumi Nakatsuji; Jun-ichi Morita; Tomonori Misaki; Yoo Tanabe

Publisher
John Wiley and Sons
Year
2007
Weight
37 KB
Volume
38
Category
Article
ISSN
0931-7597

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Water Solvent Method for Esterification
Water Solvent Method for Esterification and Amide Formation between Acid Chlorides and Alcohols Promoted by Combined Catalytic Amines: Synergy between N-Methylimidazole and N,N,N′,N′-Tetramethylethylenediamine (TMEDA)
✍ Hidefumi Nakatsuji; Jun-ichi Morita; Tomonori Misaki; Yoo Tanabe 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB

## Abstract An efficient method for esterification between acid chlorides and alcohols in water as solvent has been developed by combining the catalytic amines, __N__‐methylimidazole and __N,N,N′,N′__‐tetramethylethylenediamine (TMEDA). The present Schotten–Baumann‐type reaction was performed by ma