Water-soluble polymer carriers. Ionically bonded substances with physiological activity
✍ Scribed by Nikola G. Todorov; Marina G. Stoyanova; Stefka Tosheva
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 148 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0887-624X
No coin nor oath required. For personal study only.
✦ Synopsis
The preparation of water-soluble polymers with physiological activity via ion bonding of low molecular weight physiologically active substances to a polymer carrier has been studied. The conditions for obtaining polymer salts of physiologically active substances with acid properties and amino-containing polymer carrier have been established. The maximum conversion degree has been determined. The polymer salts have been characterized by potentiometric titration, 31 P-NMR and IR spectroscopy, and elemental analysis. The stability of the salts and the immobilization rate of the low molecular weight physiologically active substances have been investigated.