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Water-Soluble Camptothecin Derivatives that Are Intrinsic Topoisomerase I Poisons

✍ Scribed by Rahier, Nicolas J.; Eisenhauer, Brian M.; Gao, Rong; Jones, Shannon H.; Hecht, Sidney M.


Book ID
126840804
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
124 KB
Volume
6
Category
Article
ISSN
1523-7060

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A Series of Tripodal Cysteine Derivative
✍ Dr. AnaΓ―s M. Pujol; Dr. Christelle Gateau; Colette Lebrun; Dr. Pascale Delangle πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 449 KB

## Abstract A series of tripodal ligands derived from nitrilotriacetic acid and extended by three converging, metal‐binding, cysteine chains was synthesised. Their ability to bind soft metal ions thanks to their three thiolate functions was investigated by means of complementary analytical and spec