Water-soluble aldehyde-bearing polymers of 2-deoxy-2-methacrylamido-D-glucose for bone tissue engineering
✍ Scribed by Victor A. Korzhikov; Solvig Diederichs; Olga V. Nazarova; Evgenia G. Vlakh; Cornelia Kasper; Evgeny F. Panarin; Tatiana B. Tennikova
- Book ID
- 102738360
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 577 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0021-8995
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✦ Synopsis
Abstract
In this study the methods of synthesis of hydrophilic aldehyde‐bearing polymers and copolymers based on 2‐deoxy‐2‐methacrylamido‐D‐glucose have been developed. Polymers with controllable aldehyde group content were synthesized via free‐radical polymerization and subsequent polymeranalogous modification. The water‐soluble polymers obtained were investigated in view of their capacity to be adsorbed on two commercial mineral supports used in bone tissue engineering. Besides, cytotoxicity of synthesized polymers was tested. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008