Water metabolism of two marsupials—the brush-tailed possum, Trichosurus vulpecula and the rock-wallaby, Petrogale inornata in the wild

In vitro hepatic metabolism of CYP3A-med

In vitro hepatic metabolism of CYP3A-mediated drugs quinine and midazolam in the common brush-tailed possum (Trichosurus vulpecula)

✍ Ping-Chuen Ho; Xiao-Xing Luo; Jackie S. Macauley; Murray R. Grigor; Sompon Wanwi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB

## Abstract This report characterizes the P450 isoenzymes involved in quinine metabolism in liver microsomes of the common brush‐tailed possum (__Trichosurus vulpecula__). The mean maximal velocity (__V__~max~) for 3‐hydroxyquinine formation in possum livers was 1,512 ± 510 pmol/mg protein/min (mal