The hydrogen-exchange reactions of peptide NH groups in lysozyme were studied by the change in the intensity of the amide I1 band in the ir spectrum. The slowest exchanging hydrogens, which are involved in intramolecular hydrogen bonding, are further divided into two groups a t lower temperatures; h
β¦ LIBER β¦
Water as ligand: Preferential binding and exclusion of denaturants in protein unfolding
β Scribed by Timasheff, Serge N.
- Book ID
- 115474220
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 859 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0006-2960
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## Abstract A statistical mechanical model was developed for use in connection with the problem of preferential binding of solvent components to proteins and of conformational transition in waterβorganic solvent systems. The model is a statistical one for the conformational transition of globular p
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