Water Activity by1H Nuclear Magnetic Resonance Spectroscopy: Application to the Study of Water Exchange in Biphasic Media

New method for the simultaneous detectio

New method for the simultaneous detection of metabolites and water in localized in vivo 1H nuclear magnetic resonance spectroscopy

✍ Wolfgang Dreher; Dieter Leibfritz 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 425 KB

## Abstract A new two‐scan method for localized ^1^H in vivo NMR spectroscopy (MRS) without water suppression (WS) is described. In one of the scans, two chemical shift selective 180° pulses are applied prior to a standard localization sequence to invert all metabolite signals upfield and downfield