Localization of a CDKN2 gene in linkage
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Steven Kazianis; Heidrun Gutbrod; Rodney S. Nairn; Brenda B. McEntire; Luis Dell
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Article
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1998
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John Wiley and Sons
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English
โ 175 KB
The Xiphophorus hybrid melanoma model represents one of the earliest reported cases of genetically regulated tumor susceptibility. Melanoma formation in Xiphophorus hybrids may be explained by the inheritance of two genes: a sex-linked oncogene, Xmrk, and a putative tumor suppressor locus, termed DI