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W1973 Constitutive Activation of Ikk/Nf-κB in Colorectal Cancer Cells Plays Critical Role in Tumor Growth and Angiogenesis

✍ Scribed by Sakamoto, Kei; Maeda, Shin; Hikiba, Yohko; Nakagawa, Hayato; Shibata, Wataru; Yanai, Ayako; Ogura, Keiji; Omata, Masao


Book ID
122068270
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
75 KB
Volume
134
Category
Article
ISSN
0016-5085

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## Abstract Nuclear factor kappa B (NFκB) is a central participant in the metastasis and chemoresistance of colorectal cancer (CRC). However, it is not fully understood to what extent NFκB contributes to induction of the metastasis‐associated matrix metalloprotease‐9 (__MMP‐9__) gene and sensitivit