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W1675 Human Telomerase Reverse Transcriptase (hTERT) Expression in Carcinogenesis of Serous Cystic Neoplasm of the Pancreas

✍ Scribed by Nakashima, Akira; Murakami, Yoshiaki; Uemura, Kenichiro; Hayashidani, Yasuo; Sudo, Takeshi; Hashimoto, Yasushi; Ohge, Hiroki; Sueda, Taijiro; Hiyama, Eiso

Book ID: 123094895
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 109 KB
Volume: 134
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(08)64249-3

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## Abstract ## BACKGROUND Lung carcinogenesis is a multistep process of accumulation of genetic changes, including loss of heterozygosity (LOH), and precedes phenotypic transformation of the bronchial mucosa. The activity of telomerase, correlating with the hTERT mRNA expression, is detectable in