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Vλ-Jλ rearrangements are restricted within a V-J-C recombination unit in the mouse

✍ Scribed by Pierre Sanchez; Bertrand Nadel; Pierre-André Cazenave


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
498 KB
Volume
21
Category
Article
ISSN
0014-2980

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Vλ2 rearranges with all functional Jλ se
✍ Siegfried Weiss; Jutta Meyer; Matthias R. Wabl 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 499 KB

We have analyzed 210 lambda-producing hybridomas derived from lipopolysaccharide-stimulated spleen cells from a single kappa-suppressed mouse. All were classified as lambda 1, lambda 2 or lambda 3 with the exception of four unusual lines. Two of these were due to V lambda 2 J lambda 1 and the other