Down-regulation of uPA and uPAR by 3,3′-
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Aamir Ahmad; Dejuan Kong; Zhiwei Wang; Sanila H. Sarkar; Sanjeev Banerjee; Fazlu
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Article
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2009
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John Wiley and Sons
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English
⚖ 295 KB
## Abstract 3,3′‐Diindolylmethane (DIM) is a known anti‐tumor agent against breast and other cancers; however, its exact mechanism of action remains unclear. The urokinase plasminogen activator (uPA) and its receptor (uPAR) system are involved in the degradation of basement membrane and extracellul