VP-16 alone and in combination with cisplatin in previously treated patients with small cell lung cancer
β Scribed by W. K. Evans; R. Feld; D. Osoba; F. A. Shepherd; J. Dill; G. Deboer
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 600 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The drug combination of mitomycin-C, cisplatin, and vinblastine was administered to 30 patients with stage III non-small-cell lung cancer. All patients had a performance status of 50% or greater, had evaluable disease, and had not received previous chemotherapy. The overall response rate was 37% wit
## Abstract STI571, or imatinib, selectively inhibits BCR/ABL, PDGFR and cβkit kinase activity. It has been reported that a large proportion of small cell lung cancer (SCLC) cell lines and tumors express cβkit and that STI571 inhibits tumor cell growth. We therefore investigated the therapeutic eff