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Von Willebrand factor: molecular size and functional activity

✍ Scribed by M. Furlan


Publisher
Springer
Year
1996
Tongue
English
Weight
248 KB
Volume
72
Category
Article
ISSN
0939-5555

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Plasma von Willebrand factor (vWF) is a multimeric protein that mediates adhesion of platelets to sites of vascular injury, however only the very large vWF multimers are haemostatically competent. Plasma vWF derives predominantly from the vascular endothelium and is of a smaller average multimer siz