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Von Willebrand factor contaminating porcine factor VIII concentrate (Hyate: C) causes platelet aggregation

โœ Scribed by Dario C. Altieri; Anna M. Capitanio; Pier Mannuccio Mannucci

Book ID
114710948
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
472 KB
Volume
63
Category
Article
ISSN
0007-1048

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Platelet activation induced by porcine f
Platelet activation induced by porcine factor VIII (HYATE:C)
โœ Chang, H.; Mody, M.; Lazarus, A.H.; Ofosu, F.; Garvey, M.B.; Blanchette, V.; Tei ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 70 KB

We studied the effects of porcine factor VIII (P-FVIII; Hyate:C) and other coagulation products employed in the management of patients with hemophilia A, on platelet activation in vitro. Exposure of normal resting platelets to P-FVIII resulted in platelet activation, as manifested by increased expre