While patients with type 2B von Willebrand's disease often exhibit thrombocytopenia, platelet morphology is typically normal. We describe a 44-year-old Jamaican man with thrombocytopenia and a history of bleeding, who had giant platelets on his peripheral blood film. Functional studies and von Wille
โฆ LIBER โฆ
von Willebrand disease type 2N: Uncovering a congenital bleeding disorder in a patient with hepatitis C, cirrhosis, and coagulopathy
โ Scribed by Andrew A. Lane; Elizabeth M. Van Cott; Bimalangshu R. Dey
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 389 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0361-8609
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## Abstract Decreased von Willebrand factor (VWF)โcleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpuraโhemolytic uremic syndrome (UpshawโSchulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we